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Last updateFri, 23 Feb 2024 1pm

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A platform to boost therapeutic modified oligonucleotides

They are one of the most promising pharmacological tools, custom-designed for diseases such as Alzheimer's, various types of cancer, or multiple sclerosis. A multicenter project, with the participation of the CSIC, aims to create the XNA-HUB platform for designing new therapeutic molecules based on modified nucleic acids. For doing this, the platform will utilize supercomputing techniques and predictive models of Artificial Intelligence.

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A new non-steroidal anti-inflammatory and immune regulator that can replace corticosteroids has been developed

Created by a team led by the CSIC and the UPV, it is capable of inhibiting the cytokine storm associated with severe inflammation while preserving innate immunity. It is a synthetic derivative of andrographolide, the active ingredient of the plant Andrographis paniculate, commonly known as kalmegh or King of Bitters. It may also be useful in the treatment of rheumatoid arthritis, Crohn's disease, lung inflammation and fatty liver disease.

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Genetically engineered stem cells to boost cancer immunotherapy

The CSIC, the Banc de Sang i Teixits de Catalunya and the Idibell have signed an agreement to research the production of CAR-NK cells, which are easier to produce than the CAR-T cells used successfully in immunotherapy. The research will test stem cell editing using two technologies patented by the CSIC. One of the goals is to create a bank of CAR-NK anti-tumour cells for immediate use.

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Scientists develop a device to quickly identify micro-organisms in an environmental sample

The device, tested in Antarctica, optimises the efficient collection of samples and allows them to be analysed in situ. The breakthrough has been made possible by combining technologies that include the use of portable equipment to obtain and analyse DNA sequences, and proprietary analysis software, which has been patented. This development may also have applications in the clinical setting and in industry.

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Knowledge-based companies to cross the Valley of Death

30 years of R+D CSIC

Knowledge-based companies help to bring scientific results from research centres to the market and society. Thirty years ago, none existed at the CSIC. Since 1999, the CSIC has promoted about 170 companies. Of these, around 60% are still active.

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