Biology & biomedicine Projects
New targets and orphan drugs for rare diseases
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02 Dec 2019
Scientists at the Centro de Investigaciones Biológicas (CIB) of the CSIC work to find out the genetic diagnosis of rare diseases related to vascular disorders and tumors, as well as to find new therapies. Their research has focused mainly on the HHT disease and the Von Hippel-Lindau syndrome, and they have found out three orphan molecules for treating the HHT disease and one for the treatment of VHL.
Artificial intelligence for the diagnosis of rare diseases related to collagen VI
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30 Oct 2019
Researchers at the Institute of Robotics and Industrial Informatics -a joint center of the CSIC and the Polytechnic University of Catalonia-, and at the Sant Joan de Déu Hospital in Barcelona, have developed a system for helping in the diagnoses of rare diseases related to deficiencies in the structure of collagen VI.
A metabolite from a drug against diabetes, a possible treatment for neurodegenerative diseases
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06 Jun 2019
MIN-102, a metabolite from a drug against diabetes, could be useful for treating some neurodegenerative diseases, as scientists think. To confirm this hypothesis, a project has been launched with the involvement of the CSIC’s Instituto de Investigaciones Biomédicas de Barcelona, the Hospital Universitari 'Sant Joan de Déu' and the University of Lleida. The research project is led by the company Mynorix Therapeutics.
Peptides effective for inhibiting cholesterol aggregation in the vascular wall
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19 Jun 2019
A work demonstrates that peptides derived from a LRP1 receptor sequence are very effective inhibiting the aggregation of LDL (low density lipoprotein, also called 'bad' cholesterol) that takes place in the vascular wall during development of atherosclerosis.
Only the introduction is translated
Fagomine, effective in long term prevention of type 2 diabetes risk factors
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- Category: Projects
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08 Oct 2018
Researchers from the Institute of Advanced Chemistry of Catalonia CSIC study the beneficial effects of natural compounds in food. According to the conclusions of a recent study, fagomine, a natural molecule, counteracts the effects of a high-fat diet.
