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Removable basket for in vitro analysis of biological tissues

The CSIC and the Miguel Hernández University have developed a basket for in vitro tissue analysis. It enables to fix the sample and allowing its transport between wells without damaging it. It has an optimised design that allows the replacement of the mesh, the maximum use of the surface of the well and an efficient use of the reagents used.

The removable basket allows for quick and easy replacement of the mesh, as the parts are snapped together. It is simple and inexpensive to manufacture, the process doesn’t require special facilities or materials and it can be easily scaled up.

In vitro tissue analysis is a very common procedure in biological laboratories, for example in immunohistochemical analysis, for which reaction well-plates are used. However, the handling process of the analysed tissue is often complex, both because of the fragility of the tissue itself and because of the small size of the samples and the wells. Moreover, the currently available baskets are not optimised to take advantage of the well surface and the reagents used, and do not allow the replacement of the meshes.

Scientists from CSIC and the Miguel Hernández University have devised a removable basket that allows the replacement of the mesh on which the tissue is deposited, making it versatile and adaptable. Moreover, its adjustment to the well has been optimised to avoid reagent leakage and to allow complete contact with the tissue. This design avoids the existence of irregular joints that can damage the tissues, allowing maximum use of the basket surface. In addition, the dimensions of the basket and the mesh are easily adaptable to any required use. 

The removable basket allows for quick and easy replacement of the mesh, as the parts are snapped together. Its design maximises the contact surface between the walls of the basket and the walls of the well, maximising the useful surface area for the analysis and avoiding inefficient use of reagents. It is simple and inexpensive to manufacture, the process doesn’t require special facilities or materials and it can be easily scaled up. Its main application is in biological laboratories, for in vitro tissue analysis and in any technique that requires the use of wells. Now, the scientific team is looking for manufacturers of biological laboratory equipment interested in licensing the patent for the commercialisation of the basket.

Contact:

Marc Escamilla
Deputy Vice-Presidency
for Knowledge Transfer -  CSIC

Tel.: 96 161 29 95
Correo-e: This email address is being protected from spambots. You need JavaScript enabled to view it.