Los esfingolípidos, lípidos con una estructura química peculiar, tienen una inesperada importancia en varios procesos de señalización celular. Algunos de ellos podría reducir muchos de los procesos nocivos derivados de una lesión del sistema nervioso central.

Un proyecto persigue encontrar compuestos que activen de forma selectiva el receptor mGlu4 y evaluar su potencial terapéutico para el tratamiento de las lesiones medulares y el dolor asociado.

Un proyecto liderado por el Instituto de Ciencia de Materiales de Barcelona del CSIC persigue la obtención de materiales electro activos nano-estructurados para desarrollar nuevos electrodos dirigidos a la estimulación y reparación del sistema nervioso central.

A patent obtained by CSIC, and two spanish universities (UAM and UPV) has been distinguished as a proxime accessit in the the madri+d best patents competition. The development, a peptide that can restore the telomerase function, is a good example of new medical research based on cellular therapies. The scientists, Rosario Perona and her team, are co-working with the company Advanced Medical Projects to transform that protein fragment into a drug.

The antioxidant enzyme SOD-3 (superoxide dismutase-3), which is produced in the human cell membrane, can help the immune system to eliminate tumour cells, as scientists found out. The discovery suggests new strategies to fight cancer.

Plants injected with virus. Left, a non resistant plant. Right, a resistant plant. Picture: CSIC. CSIC scientists at the the Centro de Edafología y Biología Aplicada del Segura (CEBAS) have developed a method to generate varieties of cucurbits (which includes species such as melon, cucumber, watermelon or pumpkins) resistant to several viral diseases. The method is based on silencing a gene of the plant wich expresses a protein used by the virus for its own replication and spreading of the infection. No foreign elements are introduced, which reduces the chance of unexpected repercussions.
Contact:
Vicepresidencia Adjunta
de Transferencia del Conocimiento /CEBAS - CSIC
Yolanda Hernando
Tel. +(34) 968 39 63 56
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Scientists from the CSIC have designed a group of anti-inflammatory compounds, derivates of resveratrol, which have been patented. An experiment to test the new molecules against ulcerative colitis has shown that they are effective in very small quantities.

Researchers from the CSIC and two spanish universities have developed new propargylamine derivatives for the treatment of neurodegenerative diseases, particularly Alzheimer's.