A research from the IQAC-CSIC has developed a new computational approach that could aid the design of more selective and potent drugs. The researchers analyze the different shapes a potential drug can adopt when binding to its target, in order to gain insights into how it works and guide the development of new compounds.
Laboratories
A great deal of effort goes into the research and synthesis of new molecules, an effort that is wasted if these molecules are ‘lost’ because they do not serve their intended purpose. This is what the new CSIC Chemolibrary seeks to do: to preserve and enhance the value of molecules synthesised in the different CSIC laboratories that may be useful for other unexplored uses.
Technological offers
A CSIC team has developed a method for recovering high value-added bismuth from the waste generated in primary copper production, which includes an integrated removal of the arsenic present. The process contributes to economic and environmental sustainability.
Success stories
The CSIC and the spin-off Bioinicia develop new products based on a new technology, already patented, that allows compounds to be encapsulated in ultra-fine fibres that melt on contact with the skin. It is based on an electro-hydrodynamic processing that increases the penetration of the active ingredients by more than ten times.
Laboratories
The certificate is granted by the Spanish National Accreditation Entity (ENAC). It makes it the first laboratory in Spain, encompassing both public and private sectors, to receive GLP certification for biocides and the first public laboratory (the fourth if private laboratories are included) to receive certification for pharmaceuticals and cosmetics.
Technological offers
The CSIC has developed a process to obtain furfuryl alcohol based on the continuous gas-phase hydrogenation of furfural with formic acid as a source of hydrogen. It uses catalysts based on metal nanoparticles that avoid metals harmful to health and the environment. Companies in the chemical or pharmaceutical sector interested in further developing the process are sought.
Technological offers
CSIC scientists have developed a new chiral zeolitic material for the asymmetric synthesis of chiral products. The scientists point out that its particular structure allows the processing of large molecules. Pharmaceutical and fine chemical companies interested in licensing the patent for the development of synthesis processes are sought.
Technological offers
Scientists at CSIC and at the University of Bologna have developed a method for the removal of calcium carbonate crystals on surface of cultural heritage and artworks by means of a light source at a specific wavelength. Industrial partners are being sought to collaborate through a patent licence agreement.
Technological offers
CSIC scientists have developed and patented an analogous molecule of the PM567 laser colorant. These compounds are stable and can attach to biomolecules by means of ‘click’ chemistry. They can be bond to very diverse molecules and their production process is easily scalable. Main applications are the biomedical ones. Companies of the chemical sector interested in their commercial exploitation are sought.
- Obtaining coltan, the “black gold” of electronics, from the waste of an abandoned mine site
- Modifying the Brain Barrier to enhance treatments against dementia
- Nanostructured lipid hydrogel in highly diluted conditions composed only by lipids and water
- Catalyst to transform and reuse CO2 and methane
- Molecular ecosystems that interact and evolve