A scientific team has developed a fluorescent probe for monitoring the function and activity of a specific transporter in mitochondria of living cells. It is the first probe that enters the mithocondria through a specific transporter (Carnitine-acylcarnitine translocase) and it could be used for the diagnosis of rare metabolic diseases.

Biomaterials obtained through cell cultures are an excellent therapeutic strategy for the treatment of damaged tissues and organs. However, their obtention still presents handicaps. CSIC scientists have developed a method that boosts the collagen synthesis and can regulate the differentiation of mesenchymal stem cells.

Scientists at the CSIC and at the Polytechnic University of Valencia have developed a system that enables cutting biological tissues in curved forms. The system is composed of a software and an accessory for being attached to the standard tool. The device offers a totally new approximation to the structural and functional studies of biological tissues.

The system is based on a nanodetector developed by scientists at the Microelectronics Institute of Madrid (IMM-CSIC). It is more sensitive than current methods and will allow and earlier detection of pathogens.

A self-powered electrochemical sensor for detection of key metabolites such as lactate, glucose, and alcohol, among others, in physiological samples, has been developed. It can be implemented on flexible substrates. Biocompatible, it is very suitable for non-invasive medical applications in the form of skin-patches or contact lenses.

CSIC and CIBER-BBN have developed an immunochemical method for diagnosis of infections produced by Staphylococcus aureus. The immunoassay is fast and efficient, with a low limit of detection and adaptable to point-of care devices.

An immunochemical method to identify infections caused by Pseudomonas aeruginosa bacterium has been developed. It is fast, has a high sensitivity and could easily be applied to different immunochemical analytical configurations of the so called Point-of-Care (PoC) devices.

The CSIC, the University of Malaga and the CIBER laboratory have obtained bio-glass for medical uses in bone regeneration and tissue engineering. These materials, called Nitri-bioglasses, can be used as temporary scaffolds in bone implants or reconstructive surgery. They biodegrade quickly and enhance the adhesion and growth of new cells.