Computational design has made it possible to create proteins that mimic the folded immunoglobulin structure of natural antibodies. They can be used as a basis for the development of tailor-made and more economical antibody-like drugs. These results open the door to the design of antibody-like proteins with tailored structures and better biophysical properties than current ones.

A project at the ICMAB-CSIC in Barcelona is using nanomaterials to improve cancer treatment. The team, led by Gerard Tobias, has won funding from the European Research Council (ERC) to explore the commercial and societal potential of the research results.

Some pollutants are known to accumulate in the body's fatty tissue. How does this affect pregnant women? there a link between weight gain and the transfer of pollutants to the newborn? A new study provides new data that can help the administration and health managers in their decision making.

A research tested in zebrafish shows the potential of photopharmacology for future heart therapies more precise and with fewer side effects. The study is published in the journal Angewandte Chemie International Edition, selected as a Hot Paper.

Direct brain administration through the carotid artery of nanomaterials carrying drugs after a stroke could be an effective method to reduce the undesirable effects in other organs, improving at the same time the arrival of the drug into the brain. A study has tested nanocapsules designed by scientists at the ICMAB-CSIC to transport drug molecules to brain areas by a micro catheter.

An international project with participation of IIBB-CSIC has identified one of the molecular mechanisms that causes the so-called “cardiac alternans”, an alteration of the cardiac rhythm that can cause ventricular fibrillation and potentially lethal cardiac arrhythmia. This finding opens a new path to the development of pharmacological treatment.

The SINGEK project is now finished. It was a project coordinated by the Institut de Ciències del Mar (ICM, by its Spanish acronym) of the CSIC, and it had as a main goal the training of young researchers in the application of single cell genomics for the study of microbial eukaryotes’ ecology and evolution. This emerging methodology also has applications in biotechnology and biomedicine.

Scientists of the IIBB-CSIC discover a new role for sphingomyelin synthase 1 enzyme in nonalcoholic steatohepatitis, an advanced stage of fatty liver disease. The work identifies SMS1 enzyme as a possible new therapeutic target.